From Harley Street to the daily routine
Inside 111 Skin

- Founded
- 2012
- Founder
- Dr. Yannis Alexandrides; full founding team not confirmed
- Origin
- London, United Kingdom
A surgeon’s formulation question
111SKIN grew from Dr. Yannis Alexandrides’ work at 111 Harley Street. Looking for skincare suited to his patients’ needs, he began developing a formula informed by his clinical experience.
The proprietary NAC Y2 complex became a foundation for that work. According to the brand’s history, interest in using the original serum beyond the clinic helped lead to the launch of 111SKIN in 2012.
Clinical inspiration, luxurious textures
The collection expanded into serums, creams and masks, carrying its clinical inspiration into a beauty ritual. Spa experiences and facial techniques provide another expression of the house’s identity.
Its character comes from this connection between a doctor’s perspective and sensory detail. The products are an introduction to the brand’s cosmetic skincare collection.
A few ways into the collection
Selected products that introduce different sides of 111 Skin.

111 Skin Y Theorem Repair Light Serum NAC Y2 1 oz
A lightweight facial serum.
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111 Skin NEW Eye lift Gel NAC Y2 0.5 oz
A gel for the eye area.
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111 Skin Deep Cleansing Oil 3.4 oz
A facial cleansing oil.
View product →Brand background: 111 Skin’s official story.