Research-led skincare built around science, education and human wellbeing.
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iS Clinical Pro-Heal Serum Advance+
iS Clinical Pro-Heal Serum Advance+ is a powerful restorative treatment designed to calm, protect, and revitalize skin that is prone to redness, sensitivity, or blemishes. This advanced formula blends a...
iS Clinical Active Serum
$58.96 – $95.64
The iS Clinical Active Serum is a fast-acting, results-driven formula celebrated as the brand’s most popular product. This powerful botanical blend iS Clinically proven to target multiple concerns at once,...
iS Clinical Cleansing Complex
$24.21 – $82.28
The iS Clinical Cleansing Complex is a lightweight gel cleanser that delivers a thorough yet gentle cleanse without stripping the skin of essential natural oils. Formulated with a balanced blend...
iS Clinical Hydra-Cool Serum
$42.23 – $123.48
The iS Clinical Hydra-Cool Serum is a refreshing, lightweight formula designed to deliver deep hydration while calming and revitalizing the skin. Infused with hyaluronic acid, soothing botanicals, and powerful antioxidants,...
iS Clinical Retinol+ Emulsion 0.3 1 oz
iS Clinical Retinol+ Emulsion 0.3 is a clinically proven, high-performance formula designed to deliver the benefits of Retinol with enhanced tolerability and effectiveness. This advanced treatment combines a botanically derived...
iS Clinical Moisturizing Complex 1.7 oz
The iS Clinical Moisturizing Complex is a rich yet lightweight moisturizer designed to deliver deep hydration, antioxidant protection, and barrier support for all skin types. Packed with a blend of...
iS Clinical Youth Intensive Creme
iS Clinical Youth Intensive Creme is a luxurious, age-defying moisturizer crafted to transform the look and feel of mature skin. This rich, protective creme delivers 24-hour hydration while smoothing fine...
iS Clinical Retinol+ Emulsion 0.1 1 oz
iS Clinical Retinol+ Emulsion 0.1 is a gentle yet effective age-defying treatment, ideal for those beginning their retinol journey or with more sensitive skin. This advanced formula features a botanical-origin...
iS Clinical Moisturizing Complex 1.7 oz
iS Clinical Moisturizing Complex is a rich yet lightweight moisturizer designed to deliver deep hydration, antioxidant protection, and barrier support for all skin types. Packed with a blend of botanicals,...
iS Clinical Super Serum Advance+
$71.10 – $156.87
iS Clinical Super Serum Advance+ is a groundbreaking, clinically proven formula that blends next-generation Vitamin C technology with powerful peptides and botanicals for unparalleled age-defying benefits. Featuring a 15% concentration...
iS Clinical Youth Serum 1 oz
The iS Clinical Youth Serum is a high-performance treatment that delivers both instant and long-term improvements to skin’s tone, firmness, and texture. This advanced formula works immediately to smooth fine...
iS Clinical Brightening Serum 0.5 oz
iS CLINICAL Brightening Serum is a fast-acting, professional-grade treatment designed to visibly reduce the appearance of uneven skin tone, discoloration, and dullness while delivering refined texture and renewed radiance. This...
iS Clinical Brightening Complex 1 oz
iS CLINICAL Brightening Complex is an advanced, hydroquinone-free skin brightening serum formulated to visibly improve uneven skin tone, discoloration, and signs of aging while delivering lasting hydration. Designed to address...
iS Clinical Cleansing Complex Polish 4 oz
The iS Clinical Cleansing Complex Polish is a lightweight, foamy gel cleanser that delivers both a deep cleanse and gentle exfoliation in one step. Formulated with eco-friendly microparticles and botanical...
iS Clinical NeckPerfect Complex 1.7 oz
The iS Clinical NeckPerfect Complex is a targeted treatment designed to lift, tighten, and smooth the delicate skin of the neck, jawline, and décolleté. Formulated with powerful antioxidants, hydrating agents,...
iS Clinical Hydra-Intensive Cooling Masque
$67.36 – $141.31
The iS Clinical Hydra-Intensive Cooling Masque is a luxurious gel treatment designed to instantly refresh, soothe, and hydrate the skin. Infused with hyaluronic acid and a blend of antioxidant-rich botanicals,...
iS Clinical GeneXC Serum
$81.49 – $102.72
The iS Clinical GeneXC Serum is an advanced age-defying treatment that provides powerful protection while helping restore and revitalize the skin. Featuring 20% L-Ascorbic Acid (Vitamin C) along with proprietary...
iS Clinical Eclipse SPF 50+
$104.17
The iS Clinical Eclipse SPF 50+ is a lightweight, antioxidant-enriched sunscreen created for both everyday use and extended outdoor activities. Combining transparent titanium dioxide and micronized zinc oxide with vitamin...
iS Clinical C Eye Serum Advance+ 0.5 oz
The iS Clinical C Eye Serum Advance+ is a powerful yet gentle treatment formulated specifically for the delicate eye area. This advanced serum combines a scientifically proven 7.5% concentration of...
iS Clinical Cream Cleanser 4 fl oz
iS CLINICAL Cream Cleanser is a lightweight, moisturizing facial cleanser that deeply cleanses the skin and pores while keeping dryness and tightness in check. Created for dry, sensitive, and compromised...
iS Clinical Pure Clarity Collection
iS Clinical Pure Clarity Collection is a complete daily skincare system created to help refine the appearance of congested, blemish-prone skin while supporting a clearer, smoother, and more balanced complexion....
iS Clinical Warming Honey Cleanser 4 oz
iS CLINICAL Warming Honey Cleanser is a rich, luxurious treatment cleanser designed to deeply cleanse, gently exfoliate, and intensely hydrate the skin while delivering a unique warming sensory experience. Formulated...
iS Clinical Extreme Protect SPF 40
The iS Clinical Extreme Protect SPF 40 is a restorative, antioxidant-rich sunscreen designed to defend skin against both environmental aggressors and sun damage. Formulated with proprietary Extremozyme technology and all-physical...
iS Clinical Firming Complex 1.7 oz
iS Clinical Is Clinical Firming Complex 50g/1.7oz supports healthier-looking hair by improving texture, volume, and overall scalp condition. This formula helps reduce the appearance of thinning while leaving hair feeling...
iS Clinical Tri-Active Exfoliating Masque
iS Clinical Tri-Active Exfoliating Masque is a high-performance treatment designed to instantly smooth, brighten, and refine the skin. Combining the power of botanical enzymes, Salicylic Acid, and eco-friendly microparticles, this...
iS Clinical Poly-Vitamin Serum
iS Clinical Poly-Vitamin Serum is an intensive revitalizing treatment that delivers essential vitamins, antioxidants, and bionutrients to restore skin health and vitality. This powerful serum deeply hydrates while improving texture,...
iS Clinical Pure Radiance Collection
iS CLINICAL Pure Radiance Collection is a complete brightening and tone-refining skincare regimen designed to minimize the appearance of dark spots, discoloration, and dullness while promoting a clearer, more luminous...
iS Clinical Extreme Protect SPF 40 8 oz
iS Clinical Extreme Protect SPF 40 is a daily broad-spectrum sunscreen that goes beyond UV protection to actively improve skin health. This professional-strength formula defends against harmful UVA and UVB...
iS Clinical Youth Lip Elixir 0.12 oz
The iS Clinical Youth Lip Elixir is a luxurious treatment that delivers intense hydration and visible rejuvenation to the lips. Formulated with powerful botanical extracts, antioxidants, and advanced hydrators, it...
iS Clinical Pure Renewal Collection 4 pc
$169.32
iS Clinical Pure Renewal Collection is a four-step regimen for skin that has stalled: congested, uneven in tone and slower to bounce back than it used to be. It runs...
iS Clinical Youth Body Serum
$29.46
iS Clinical Youth Body Serum is a refreshing, lightweight serum mist designed to deeply hydrate, nourish, and protect the skin. Unlike traditional body creams, this advanced formula absorbs quickly, delivering...